Welcome to our dedicated page for Amgen news (Ticker: AMGN), a resource for investors and traders seeking the latest updates and insights on Amgen stock.
Amgen Inc. (NASDAQ: AMGN) is a leading American multinational biopharmaceutical company, established in 1980 and headquartered in Thousand Oaks, California. As one of the largest independent biotechnology companies globally, Amgen specializes in discovering, developing, manufacturing, and delivering innovative human therapeutics. The company focuses on areas of high unmet medical need and leverages its expertise in advanced human genetics to develop solutions that dramatically improve people's lives.
Amgen's portfolio includes a range of flagship drugs such as red blood cell boosters Epogen and Aranesp, immune system enhancers Neupogen and Neulasta, and treatments for inflammatory diseases like Enbrel and Otezla. Additionally, the company has a strong presence in the oncology sector with products like Vectibix, Prolia, Evenity, and Kyprolis. Notably, the acquisition of Onyx Pharmaceuticals bolstered Amgen's oncology portfolio.
Recent launches include innovative therapies such as Repatha for cholesterol management, Aimovig for migraines, Lumakras for lung cancer, and Tezspire for asthma. In 2023, Amgen's acquisition of Horizon Therapeutics introduced several rare-disease drugs to its portfolio, including Tepezza for thyroid eye disease. Amgen also continues to expand its biosimilar portfolio, reinforcing its commitment to making advanced treatments more accessible.
Amgen's financial health is robust, with significant growth in revenues and product sales. The company's strategic partnerships and acquisitions have continually strengthened its market position. For instance, the recent Phase 3 SPROUT study demonstrated the efficacy and safety of Otezla in pediatric patients, highlighting Amgen's ongoing commitment to addressing various health needs. Furthermore, the company’s dedication to innovation is evident from its extensive pipeline of investigational drugs targeting various conditions.
Amgen has been acknowledged for its workplace culture and environmental initiatives, being named one of
deCODE genetics, an Amgen subsidiary, has achieved a significant breakthrough by creating the first complete recombination map of the human genome, published in Nature. The research provides important insights into how DNA is mixed during reproduction, marking a major advancement in understanding genetic diversity and its impact on health and fertility.
The groundbreaking map includes previously difficult-to-detect shorter-scale shuffling of grandparental DNA and identifies areas devoid of major reshuffling. This research helps explain why some pregnancies fail and how the genome maintains a balance between diversity and stability. The study reveals important gender differences in recombination patterns, noting that women experience increased frequency of non-crossover recombinations with age, potentially explaining higher pregnancy risks in older mothers.
This advancement is particularly relevant for fertility research, as recombination errors can lead to serious reproductive issues affecting approximately one in ten couples worldwide. The study also demonstrates that mutations are elevated near DNA mixing regions, providing new understanding of human evolution and individual health outcomes.
Amgen (NASDAQ:AMGN) has received FDA approval for LUMAKRAS® (sotorasib) in combination with Vectibix® (panitumumab) for treating adult patients with KRAS G12C-mutated metastatic colorectal cancer (mCRC). The approval is based on the Phase 3 CodeBreaK 300 study results.
The study showed that LUMAKRAS (960 mg daily) plus Vectibix demonstrated a median progression-free survival of 5.6 months compared to 2 months with standard care, and an overall response rate of 26% versus 0%. The KRAS G12C mutation occurs in approximately 3-5% of colorectal cancers.
The most common adverse reactions (≥20%) include rash (87%), dry skin (28%), diarrhea (28%), stomatitis (26%), fatigue (21%), and musculoskeletal pain (21%).
Amgen (NASDAQ:AMGN) has announced its participation in the 2025 J.P. Morgan Healthcare Conference. The presentation is scheduled for Monday, January 13, 2025, at 3:00 p.m. PT, featuring Robert A. Bradway, chairman and chief executive officer of Amgen.
The event will be accessible through a live webcast simultaneously available to investors, news media, and the general public. The presentation can be accessed through Amgen's website (www.amgen.com) under the Investors section, along with other selected management presentations from investor and medical conferences. The webcast recording will remain available for replay for a minimum of 90 days following the event.
Asher Biotherapeutics has entered into a clinical trial collaboration and supply agreement with Amgen (NASDAQ:AMGN) to evaluate the combination of etakafusp alfa (AB248) with IMDELLTRA® (tarlatamab) in patients with extensive-stage small cell lung cancer (ES-SCLC).
The collaboration will focus on testing Asher Bio's CD8+ T cell targeted interleukin-2 immunotherapy alongside Amgen's DLL3-targeting Bispecific T-cell Engager therapy. Amgen will sponsor and conduct a global Phase 1b study to evaluate the safety and early efficacy of the combination therapy. Asher Bio will maintain full ownership of etakafusp alfa and provide it to Amgen at no cost.
Amgen (NASDAQ:AMGN) has announced its quarterly dividend for the first quarter of 2025. The company's Board of Directors has declared a dividend of $2.38 per share. Shareholders who are recorded as stockholders by the close of business on February 14, 2025, will receive the dividend payment on March 7, 2025.
Amgen's BLINCYTO (blinatumomab) has shown significant improvement in disease-free survival when added to chemotherapy for newly diagnosed pediatric patients with B-cell acute lymphoblastic leukemia (B-ALL). In a Phase 3 study, the three-year disease-free survival rate was 96.0% for patients receiving BLINCYTO plus chemotherapy, compared to 87.9% for chemotherapy alone, representing a 61% reduction in disease relapse risk.
The study met its primary endpoint early, leading to early termination of randomization due to clear benefits. For standard-risk average patients, three-year survival was 97.5% with BLINCYTO versus 90.2% with chemotherapy alone. For high-risk patients, rates were 94.1% versus 84.8%. Safety results aligned with BLINCYTO's known profile, showing minimal severe side effects.
Amgen (NASDAQ: AMGN) has announced a $1 billion expansion to establish a second drug substance manufacturing facility in Holly Springs, North Carolina. This investment builds upon a previous $550 million commitment, bringing the total planned investment to over $1.5 billion.
The expansion will create 370 new jobs in the region and incorporate cutting-edge technologies and sustainable practices. The new facility, alongside the existing one, will strengthen Amgen's global biomanufacturing network and support the company's ability to meet growing demand for its innovative therapies.
Amgen (NASDAQ:AMGN) has announced its participation in Citi's 2024 Global Healthcare Conference on Thursday, Dec. 5, 2024, at 9:30 a.m. ET. The company will be represented by three executive leaders: Peter Griffith (EVP and CFO), Jay Bradner (EVP of R&D and CSO), and Susan Sweeney (EVP of Obesity and Related Conditions), who will engage in a fireside chat.
The presentation will be webcast live and made accessible to investors, media, and the public through Amgen's website. The webcast recording will remain available for replay on www.amgen.com under the Investors section for at least 90 days following the event.
Amgen (NASDAQ:AMGN) has announced its participation in the 7th Annual Evercore HealthCONx Conference on December 4, 2024, at 10:00 a.m. ET. Three executive leaders will participate in a fireside chat: Peter Griffith (EVP and CFO), Jay Bradner (EVP of Research and Development, CSO), and Susan Sweeney (EVP of Obesity and Related Conditions).
The presentation will be accessible through a live webcast on Amgen's website (www.amgen.com) under the Investors section. The webcast will remain available for replay for at least 90 days following the event.
Amgen (NASDAQ:AMGN) reported positive 52-week Phase 2 study results for MariTide, a monthly or less frequent subcutaneous treatment for obesity. The drug achieved ~20% average weight loss in people with obesity/overweight without Type 2 diabetes, and ~17% weight loss in those with Type 2 diabetes, alongside a 2.2 percentage point reduction in HbA1c. No weight loss plateau was observed, suggesting potential for further weight reduction. The treatment showed improvements in cardiometabolic parameters and had manageable gastrointestinal side effects. The discontinuation rate in dose escalation arms was ~11%. Amgen announced the initiation of MARITIME, a Phase 3 program for obesity and related conditions.
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